EXIT OF PEDIATRIC PRE-B ACUTE LYMPHOBLASTIC LEUKAEMIA CELLS FROM THE BONE MARROW TO THE PERIPHERAL BLOOD IS NOT ASSOCIATED WITH CELL MATURATION OR ALTERATIONS IN GENE EXPRESSION

turbo air m3f72-3-n Abstract Background Childhood pre-B acute lymphoblastic leukemia (ALL) is a bone marrow (BM) derived disease, which often disseminates out of the BM cavity, where malignant cells to a variable degree can be found circulating in the peripheral blood (PB).Normal pre-B cells are absolutely dependent on BM stroma for survival and di

Synthetic aperture radar (SAR) sliding spotlight work mode can achieve high resolutions and wide swath (HRWS) simultaneously by steering the radar antenna beam.This paper aims iphone 14 price texas to obtain well focused images using sliding spotlight mode with the Chinese Gaofen-3 SAR sensor.We proposed an integrated imaging scheme with sliding sp

Detecting morphed face images has become an important task to maintain the trust in automated verification systems based on facial images, e.g., at automated border control gates.Deep Neural Network (DNN)-based detectors have shown remarkable results, but without further investigations their decision-making process is not transparent.In contrast to

Protein ashy bines protein powder turnover is vital to cellular homeostasis.Many proteins are degraded efficiently only after they have been post-translationally "tagged" with a polyubiquitin chain.Ubiquitylation is a form of Post-Translational Modification (PTM): addition of a ubiquitin to the chain is catalyzed by E3 ligases, and removal of ubiqu